Close this search box.


Pharma Clean Room Results for Velocity Contour

Project Brief

This case study showcases the successful application of Computational Fluid Dynamics (CFD) analysis in evaluating temperature, pressure, velocity, relative humidity, particle generation, and tracking with human motion inside a cleanroom for the pharmaceutical industry.

Challenges and Objectives

The client required a comprehensive analysis of their cleanroom to ensure compliance with strict pharmaceutical industry standards. They aimed to evaluate the performance of the cleanroom in maintaining cleanliness, temperature, and humidity levels while accommodating human movement and equipment heat load.


1.Developed a 3D model of the cleanroom.
2.Defined boundary conditions including heat load in equipment, partitions, and walls, as well as inlet and outlet conditions for pressure, velocity, temperature, and relative humidity.
3.Integrated particle generation and tracking details along with human motion parameters.
CFD Analysis:
1.Conducted 3D steady state and dynamic CFD analysis using the defined boundary conditions.
2.Analyzed temperature distribution due to heat dissipation, identified hotspots in the system, and assessed velocity and relative humidity distribution inside the cleanroom.
3.Tracked particles to determine adherence to acceptance criteria.


1.Successfully identified areas of improvement in the cleanrooms design and operation.
2.Optimized temperature distribution, ensuring uniformity and reducing hotspots.
3.Improved ventilation efficiency, leading to enhanced air quality and particle control.
4.Enhanced understanding of human motion impact on cleanroom environment.
5.Overall, the analysis contributed to the enhancement of the cleanrooms’ performance and compliance with industry standards.


Through the implementation of 3D steady state and dynamic CFD analysis, the project effectively evaluated and optimized the cleanrooms’ performance, leading to improved air quality, temperature distribution, and particle control in the pharmaceutical manufacturing environment. The insights gained from the analysis provided valuable recommendations for enhancing the cleanrooms’ design and operation, ultimately ensuring compliance with industry regulations and standards.

let's work together

Lets Work together to build awesome engineering marvel

Its easy, we need some of your details and we shall get in touch with you at the earliest.